Sleep Apnea Induced By Insulin Resistance

A growing body of evidence points to insulin resistance in humans as one cause of sleep apnea. When researchers fed nonobese rats a high-fat diet they developed insulin resistance and sleep apnea.  A second group of rats fed the same diet but given metformin (which increases insulin receptor sensitivity), prevented the elevated insulin levels and the sleep apnea.PositiveTip: Choose…

Read MoreLong right arrow

Diabetics on Metformin Need to Monitor Vitamin B-12

Metformin is the most commonly prescribed oral medication for those with type 2 diabetes. A new Dutch study has again linked this medication with significantly lower vitamin B-12 serum levels. These researchers also found the blood homocysteine levels were also significantly higher, causing an increased risk of cardiovascular disease. B-12 deficiency can lead to anemia, neuropathy, and cognitive…

Read MoreLong right arrow

Popular Diabetic Medication Lowers Vitamin B12 Levels

A Canadian prospective case-control study has found that Vitamin B12 levels were significantly lower in type-2 diabetics taking metformin than those not taking it (231 vs. 486 pmol/L). Those on metformin also had significantly higher levels of two markers of B12 deficiency (homocysteine and methylmalonic acid) along with increased severity of neuropathy. This B12 deficiency may…

Read MoreLong right arrow

Lifestyle Modification Delays Onset of Diabetes at Least Ten Years

The Diabetes Prevention Program reported in 2002 that compared with placebo, an intensive lifestyle intervention program or oral medications in 3200 individuals with impaired glucose metabolism lowered the incidence of diabetes during the three years of the study by 58% and 31%, respectively. Most of these participants were then enrolled in seven additional years of…

Read MoreLong right arrow