Timing is Vital


Changes in sleep timing as in jet lag and shift work has been found to suppress the process of RNA transcription and translation. Twenty-two healthy volunteers were subjected to three 28-hour days (i.e. sleep progressively delayed by 4 hours each day). This mistimed sleep (not sleep restriction) decreased the rhythmic transcripts in the blood transcriptome from 6.4% to 1.0%. These finding help account for why disordered physiological rhythms induce adverse physical and mental health effects.

PositiveTip: Keep your sleep-wake cycle regular for optimum health.