NSAIDs and Risk


A large meta-analysis revealed that some commonly used nonsteroidal anti-inflammatory medications (NSAIDs) increase the risk of major vascular events (mostly heart attacks) by almost one-third. Up to now it has not been clear if high doses of the traditional NSAIDs such as ibuprofen, naproxen, and diclofenac (2400, 1000 and 150 mg daily, respectively) increased risk. Patients need to work with their physicians in determining what they should be taking to minimize risk while effectively managing their pain.

PositiveTip: My father (a pharmacologist) always said, "If you don't absolutely need it, don't take it!"