Many people who are overweight or obese often blame it on their genes. In a meta-analysis of nearly 10,000 subjects, researchers from England found even those with genetic risk factors for obesity respond as well as anyone else to diet and exercise. This data strongly suggests that obesity-linked genes do not affect the ability to lose weight.
PositiveTip: Don't blame your genes. While your genes may increase your risk of being fat, your choices of healthful lifestyle change make is possible to lose weight!