Exercise can help reverse insulin resistance.

High-fat diets raise enzyme levels, reducing insulin's normal physiologial function. A study on rats has shown exercise inhibits the diet-induced insulin resistance that normally occurs.

PositiveTip: Exercise will help to normalize your insulin and other hormones. Daily walking is excellent, economical, and has a very low risk of injury.

Source: http://jp.physoc.org/content/577/3/997.full.pdf

High fat and sugar intake may change hormone secretion toward weight gain.

Diets with higher levels of fat and sugar appear to change hormone levels in favor of weight gain. Consuming high fat and sugar foods increases insulin and ghrelin, two hormones that are related to weight gain while decreasing leptin, which aids in weight loss.

PositiveTip: Consuming a vegetarian or Mediterranean type diet can aid efforts to lose weight.