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FTO gene

Obesity Gene Switched Off by Exercise

In 2007, the FTO (fat, mass, and obesity) gene was discovered which predisposes humans to develop obesity. This obesity gene is found in about 75% of people from Europe, and African Americans but only 44% of Asians.

People with one copy of the FTO gene have an increased risk of obesity of 30%. A person with two copies of the FTO gene have a risk of obesity of 70%. Dr. Ruth Loos recently did an analysis of dozens of studies that included over 200,000 individuals. 

Some of the people who exercised regularly—the equivalent of walking for 30 minutes 5 days a week—turned off their obesity genes. There was an across the board 30% reduction in obesity for those who exercised, no matter how many copies of the FTO gene they had.